Preparation of riboflavin, and 4,5-dimethyl-N-(D)-ribityl-2-(O-a

Details Preparation of riboflavin, and 4,5-dimethyl-N-(D)-ribityl-2-(O-a Preparation of riboflavin, and 4,5-dimethyl-N-(D)-ribityl-2-(O-a

1985-05-03

1987-04-07

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

534858, C07D57514, C07C10706

Patent

active

046562753

ABSTRACT:
An improved process for the preparation of riboflavin by condensation of a 4,5-dimethyl-N-(D)-ribityl-2-phenylazoaniline derivative with barbituric acid in the presence of an acidic condensing agent in an organic solvent, wherein a 4,5-dimethyl-N-(D)-ribityl-2-(o-alkoxyphenylazo)-aniline of the formula IIa ##STR1## where R is alkyl of 1 to 4 carbon atoms, in particular methyl, is reacted with barbituric acid, as well as the novel intermediates of the formula IIa.

REFERENCES:
patent: 2237074 (1941-04-01), Karrer
patent: 2350376 (1944-06-01), Tishler et al.
patent: 2370093 (1945-02-01), Tishler et al.
patent: 2807611 (1957-09-01), Howe
Tul'chinskaya et al., Chemical Abstracts, vol. 101, 37923h (1984).
Tishler et al., "Journal of American Chemical Society", vol. 69, (1947), pp. 1487-1492.
Korte et al., Liebigs Ann. Chem. 615, (1958), pp. 94-99.
Berezowski, J. of Gen. Chem. USSR, vol. 31, No. 10, pp. 3444-3448, (1961).
"Ullmanns Encyclopedia of Technical Chemistry 23", Verlag Chemie, Weinheim-Berstr., 4 edition, 1983, p. 666.
"Riboflavin", Plenum Press, New York, 1975, pp. 318-319, (Rivlin).

Affiliated with

Also associated with

Rating

Preparation of riboflavin, and 4,5-dimethyl-N-(D)-ribityl-2-(O-a does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of riboflavin, and 4,5-dimethyl-N-(D)-ribityl-2-(O-a, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of riboflavin, and 4,5-dimethyl-N-(D)-ribityl-2-(O-a will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1087693