Substituted tetralins, chromans and related compounds in the tre

Details Substituted tetralins, chromans and related compounds in the tre Substituted tetralins, chromans and related compounds in the tre

1989-08-04

1991-10-22

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514212, 540492, 544125, 544333, 546174, 546176, C07D40112, C07D40512, A61K 3147, A61K 31505

Patent

active

050596098

ABSTRACT:
Substituted tetralins, chromans and related compounds which, by inhibiting 5-lipoxygenase enzyme and/or blocking leukotriene receptors, are useful in the prevention or treatment of asthma, arthritis, psoriasis, ulcers, myocardial infarction and related disease states in mammals, pharmaceutical compositions thereof, a method of treatment therewith, and to intermediates useful in the synthesis thereof.

REFERENCES:
patent: 4183945 (1980-01-01), Doria et al.
patent: 4202985 (1980-05-01), Hoehn
patent: 4363811 (1982-12-01), Evans et al.
patent: 4576949 (1986-03-01), Smith
patent: 4661499 (1987-04-01), Young et al.
patent: 4661596 (1987-09-01), Kreft, III et al.

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