Amino disulfides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514397, 514410, 548422, 548336, 546271, A61K 3144, A61K 3140, C07D48714

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active

048032123

ABSTRACT:
The present invention refers to mitomycin analogs containing a disulfide group. These compounds are mitromycin C derivatives in which the 7-amino group bears an organic substituent incorporating a disulfide group. The compounds are inhibitors of experimental animal tumors.

REFERENCES:
patent: 3332944 (1967-07-01), Cosulich et al.
patent: 3420845 (1969-01-01), Matsui et al.
patent: 3450705 (1969-06-01), Matsui et al.
patent: 3514452 (1970-05-01), Matsui et al.
patent: 3660578 (1972-05-01), Hata et al.
patent: 4231936 (1980-11-01), Nakano et al.
patent: 4268676 (1981-05-01), Remers
Iyengar et al., J. Med. Chem., vol. 26, (1983) pp. 16-20.
Iyengar et al., Abst. of Papers 183rd Annual Meeting of the A.C.S. Mar. 1982 No. Medi 72.
Matsui et al., J. Antibiotics, XXI (1968), pp. 189-198.
The Merk Index, 9th ed. p. 1067 (8003) and p. 364 (2780).
J. Amer. Chem. Soc. 84, 3185-3187 (1962) J. S. Webb et al.
The Journal of Antibiotics, XXI, 189-198 (1968) Matsui et al.
J. Med. Chem. 14, 103-109 (1971) Kinoshita et al.
J. Med Chem. 24, 975-981 (1981) Iyengar et al.
Physicians' Desk Reference 35th Edition, 1981, pp. 717-718.
Iyengar et al.-Abstracts of Papers 183rd Annual Meeting of the American Chemical Society, Mar. 1982, No. MEDI 72.
C. A. Claridge et al.-Abst. of the Annual Meeting of Amer. Soc. for Microbiology 1982. Abs. 028.
J. Med. Chem. 1983, 26, 16-20 Iyengar et al.
Iyengar et al. Abstracts of Papers, 185th Annual Meeting of the American Chemical Society, Mar. 1983, No. MEDI 82.
Farmdoc No. 56227 D/31.
American Association of Cancer Research Poster Material presented May 25, 1983 in San Diego, California.
Shirahata et al., J. Am. Chem. Soc., 1983 105, 7199-7200.

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