Substituted and bridged tetrahydropyridines useful as calcium en

Details Substituted and bridged tetrahydropyridines useful as calcium en Substituted and bridged tetrahydropyridines useful as calcium en

1984-05-29

1986-04-01

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 80, 546 89, 546 92, A61K 31455, C07D49108, C07D49508

Patent

active

045798516

ABSTRACT:
Substituted dihydropyridines and substituted and bridged tetrahydropyridines are disclosed which are useful as calcium entry blockers.

REFERENCES:
Hof, R. P. "Calcium Antagonist and the Peripheral Circulation:" Br. J. Pharmac., 78, 375-394 (1983).
Hof, R. P. "The Calcium Antagonists PY 108-068 and Verapanil Diminish the Effects of Angiotensin II:" Br. J. Pharmac., 82, 051-060 (1984).
Van Meel, J. C. A., et al. "The Inhibitory Effect of Newer Calcium Antagonists" Arch. Int. Pharmacodyn, 260, 206-217 (1982).
Schramm, M. "Novel Dihydropyridines with Positive Inotropic Action" Nature vol. 303 Jun. 9, 1983 pp. 535-537.
Bossert, F. et al. "4-14 Aryldihydropyridines" Angew. Chem. Ed. Engl. 20, pp. 762-769 (1981).

Affiliated with

Also associated with

Rating

Substituted and bridged tetrahydropyridines useful as calcium en does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted and bridged tetrahydropyridines useful as calcium en, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted and bridged tetrahydropyridines useful as calcium en will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1084638