Process for the manufacture of enol derivatives

Details Process for the manufacture of enol derivatives Process for the manufacture of enol derivatives

1985-08-19

1986-04-01

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602454, 2603303, 2603309, 546256, 546270, 546271, 546275, 546277, 546278, 546279, 546280, C07D20508, C07D40112, C07D40512, C07D41712

Patent

active

045796840

ABSTRACT:
The invention concerns a process for the manufacture of 7.beta.-amino-3-cephem-3-ol-4-carboxylic acid compounds by ring closure of esters of 2-[4-(substituted-thio)-3-acylamino-2-oxoazetidin-1-yl]-3-substituted-amin o-crotonic acids and solvolysing the enamino group in the resulting 7.beta.-acylamino-3-substituted-amino-cephem-4-carboxylic acid esters.

REFERENCES:
patent: 4079181 (1978-03-01), Tsuji
patent: 4130557 (1978-12-01), Hamashima
patent: 4147864 (1979-04-01), Woodward et al.
patent: 4160085 (1979-07-01), Tsuji
patent: 4293462 (1981-10-01), Woodward et al.
Hamashima II, Chem. Abs. 87, 5999p, (1977).

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