Antimicrobial (N-1-octyl-4(1H)-pyridinylidine)octanamine and aci

Details Antimicrobial (N-1-octyl-4(1H)-pyridinylidine)octanamine and aci Antimicrobial (N-1-octyl-4(1H)-pyridinylidine)octanamine and aci

1984-09-12

1986-07-01

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546304, C07D21374, A61K 3144

Patent

active

045980829

ABSTRACT:
N-[1-(alkyl or arylmethyl)-4(1H)-pyridinylidine]-alkanamine and pharmaceutically acceptable acid addition salts thereof, for example, N-(1-octyl-4(1H)-pyridinylidine)octanamine monohydrochloride salt, which are useful as antimicrobial agents, especially on living tissues and nonliving surfaces and most especially against pathogenic dental microbes, and a process for preparation, methods of use and compositions thereof are disclosed.

REFERENCES:
patent: 4206215 (1980-06-01), Bailey
Merck Index, 9th Edition (1976) p. 254.
Landquist, Journal of the Chemical Society, Perkin Transactions I, No. 4, pp. 454-456, 1976.

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