Mutant strain of Escherichia coli and its use for the preparatio

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide

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4351723, 435175, 435253, 435849, 935 14, 935 73, C12P 2102, C12N 1500, C12N 1118, C12N 120

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045980462

ABSTRACT:
The present invention relates to a new mutant strain of Escherichia coli and its use for the preparation of glutathione.
The present invention is based upon the discovery that a certain mutant strain which we have induced from a wild strain of Escherichia coli is capable of accumulating large amounts of glutathione and an enzyme system for the synthesis of glutathione in the cultured broth.
The new mutant strain is preferably Escherichia coli designated Escherichia coli RC 912 p (FERM-BP No. 48).

REFERENCES:
patent: 4237224 (1980-12-01), Cohen et al.

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