Process of preparing michellamine compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D40104

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active

056544324

ABSTRACT:
The present invention provides new antiviral compounds, i.e., michellamines and derivatives and pharmacologically acceptable salts thereof, methods for isolating such antiviral compounds from a plant species of the genus Ancistrocladus, antiviral compositions containing such antiviral compounds, and methods of using such antiviral compounds for treating patients with viral infections. The antiviral compounds of the present invention inhibit the reproduction and cytopathicity of human acquired immunodeficiency viruses.

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Stuart-Harris et al., in The Background to Chemotherapy of Virus Diseases, Chapter 5, 76-77 (Charles C. Thomas Publishers, Springfield, IL, 1965).
Weislow et al., J. National Cancer Institute, 81 (8), 577-586 (Apr. 19, 1989).

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