Preparation of beta-methyl carbapenem intermediates

Details Preparation of beta-methyl carbapenem intermediates Preparation of beta-methyl carbapenem intermediates

Filed on

1995-05-04

Date issued

1997-08-05

Examiner

Berch, Mark L.

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

C07D20508, C07D40504, C07F 710

Type

Patent

Status

active

Patent number

056544243

Description

ABSTRACT:
The present invention is directed to a process of making a Beta-methyl carbapenem intermediate of formula VI from a compound of formula I ##STR1## wherein R and P' are protecting groups R.sup.1 is a methylmalonic acid ester and Nu is a nucleophilic group. Process intermediates are also disclosed.

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