Amine derivatives

Details Amine derivatives Amine derivatives

1991-04-16

1997-08-05

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142252, 5142278, 5142282, 5142298, 5142305, 5142332, 5142355, 514298, 514300, 514312, 514314, 514318, 514322, 514334, 514339, 514340, 514343, 514354, 540451, 540461, 544102, 544105, 544124, 544122, 544128, 544129, 544141, 544142, 544143, 546109, 546121, 546122, 546123, 546153, 546160, 546193, 546194, 546257, 546290, 546299, 546304, 546347, A01N 4362, A01N 4340, C07D21192, C07D21168

Patent

active

056542984

ABSTRACT:
This invention concerns novel aminopyridinium compounds of the formula I wherein R.sup.1, R.sup.2, R.sup.3, R.sup.5 and R.sup.6 are selected from the following combinations: ##STR1## (a) one of R.sup.2 and R.sup.6 is a basic group selected from amino, alkylamino, dialkylamino of up to eight carbon atoms, pyrrolidino, piperidino and morpholino, or is alkyl, alkenyl, alkoxyalkyl, alkoxy, alkylthio, phenyl, phenylalkyl, cycloalkyl or cycloalkylalkyl; and the other of R.sup.2 and R.sup.6 is hydrogen, alkyl or one of the above defined basic groups;

REFERENCES:
patent: 2748124 (1956-05-01), Burtner
patent: 2845425 (1958-07-01), Whitehead et al.
patent: 4067874 (1978-01-01), Ursprung
patent: 4339453 (1982-07-01), Grier et al.
patent: 4503050 (1985-03-01), Wade
patent: 4725600 (1988-02-01), Takaya et al.
patent: 4859663 (1989-08-01), Greve et al.
patent: 5019565 (1991-05-01), Baker et al.
Archives of Biochemistry and Biophysics, vol. 280, No. 2, 1 Aug. 1990, pp. 274-283.
J. Het. Chem 9(4), 783-7. Aug. 1972.
J. Am. Chem. Soc. 105, 1983, 5661-5664.
J. Am. Chem. Soc., 103, 1981, 6148-6151.
Y.G. Kagaku"Preparation of 1-Phenyl-Polyhydro-s-Triazines" Org. Syn. Chem., 34(6), 417-424, (1976); English Translation (Chemical Abstracts, vol. 86, No. 9, Abstr. No. 55393M).
Chemical Abstracts, vol. 80, No. 1, Abstr. No. 3472T, Jan. 7, 1974.
Chemical Abstracts, vol. 80, No. 1, Abstr. No. 3471S, Jan. 7, 1974.
Chemical Abstracts, vol. 58, No. 2, No. 1451e, Jan. 21, 1963.
Chemical Abstracts, vol. 111, No. 17, No., 153834K, Oct. 23, 1989.
Chemical Abstracts, vol. 79, No. 17, No. 105194a, Oct. 29, 1973.
Chemical Abstracts, vol. 105, No. 15, No. 133849s, Oct. 13, 1986.
Chemical Abstracts, vol. 106, No. 17, No. 138408c, Apr. 27, 1987.
Chemical Abstracts, vol. 69, No. 17, No. 67335f, Oct. 21, 1968.
Chemical Abstracts, vol. 86, No. 23, No. 171370u, Jun. 6, 1977.
Chemical Abstracts, vol. 108, No. 3, No. 21816j, Jan. 18, 1988.
W.A. Denny et al. "Potential Antitumor Agents. 29. Quantitative Structure-Activity Relationships for the Antileukemic Bisquaternary Ammonium Heterocycles" J. Med. Chem., 22(2), 134-50 (1979).
G.J. Atwell et al. "Potential Antitumor Agents. VIII. Bisquaternary Salts" J. Med. Chem., 11, 690-4 (1968).

Affiliated with

Also associated with

Rating

Amine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1074979