Substituted phenylacetic acid amide compounds

Details Substituted phenylacetic acid amide compounds Substituted phenylacetic acid amide compounds

1980-10-03

1983-12-20

Reamer, James H.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

560 39, 560 41, 560 38, 562448, 562449, 562450, 424319, A61K 3124, C07C10144

Patent

active

044217650

ABSTRACT:
Phenylacetic acid amide compounds of the formula ##STR1## in which R.sub.1 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R.sub.2 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R.sub.3 is hydrogen, lower alkyl, lower alkoxy or halogen having an atomic number of not more than 35 and R.sub.4 is hydrogen, lower alkyl, lower alkoxy or halogen having an atomic number of not more than 35, and in which R.sub.5 is a radical of aliphatic character containing the group R.sub.6, R.sub.6 and R.sub.7 are each hydrogen or together are a divalent aliphatic radical and the group of the formula --C(.dbd.O)--R.sub.8 (Ia) is a carboxyl group, which can be functionally modified, and their salts are useful as anti-inflammatory agents.

REFERENCES:
patent: 3536758 (1970-10-01), Sallmann et al.
patent: 3652762 (1972-03-01), Sallmann
patent: 3897782 (1975-07-01), Baltze et al.

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