Phosphate and thiophosphate protecting groups

Details Phosphate and thiophosphate protecting groups Phosphate and thiophosphate protecting groups

1999-03-16

2000-09-19

Leary, Louise N.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 111, 536 41, 536 254, 536 2531, C07H 1904, C07H 100

Patent

active

06121437&

ABSTRACT:
Novel phosphorus protecting groups, intermediates thereof, and synthetic processes for making the same are disclosed. Oligomeric compounds are prepared through the protection of one or more internucleosidic phosphorus functionalities, preferably followed by oxidation and cleavage of the protecting groups to provide oligonucleotides.

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