Method of hybridization using oligonucleotide probes

Details Method of hybridization using oligonucleotide probes Method of hybridization using oligonucleotide probes

1995-05-23

1997-08-05

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 5, 435 912, 536 243, 536 2432, 536 2433, C12Q 168, C12Q 170, C07H 2102, C07H 2104

Patent

active

056541473

ABSTRACT:
An improved method of hybridization with oligonucleotide probes using tetramethylammonium chloride is provided. The method is useful for screening mixtures of DNA sequences, including libraries of high DNA sequence complexity, with a single oligonucleotide probe or a pool of probes representing all possible codon choices for a short amino acid sequence.

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