Biomaterial based on collagen and its application

Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...

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424 931, 424 933, 424 937, 4352401, 4352402, 43524021, 43524023, 435240243, 530356, 530402, 623 15, A61K 3536, C12N 506, C12N 508, A61F 210

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056541350

ABSTRACT:
Biomaterial based on collagen comprises, intimately associated, a support forming a dermal substitute, said support comprising a layer based on type IV collagen and an epidermal epithelium having differentiated cells obtained by growing epidermal cells on said support.

REFERENCES:
Bosca et al., J. Inv. Derm., vol. 91, pp. 136-141, 1988.
Wilke et al; "Human keratinocytes adhere to a unique heparin-binding peptide sequence within the triple helical region of type IV collagen"; Journal of Investigative Dermatology, vol. 95,No. 3, pp. 264-270, Sep. 1990.
Tinois et al; "Growth and differentiation of human keratinocytes on extracellular matrix"; Biological Abstracts, vol. 84, No. 8, pp. AB-565, Abrege No. 88152, 1987.
Tinois et al; "In vitro and post-transplantation differentiation of human keratinocytes grown on the human . . . "; Experimental Cell Research, vol. 193, pp. 310-319, 1991.

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