Pharmaceutical compositions for transmucosal delivery of peptide

Details Pharmaceutical compositions for transmucosal delivery of peptide Pharmaceutical compositions for transmucosal delivery of peptide

1996-07-17

1997-08-05

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

436829, A61K 9127

Patent

active

056540000

ABSTRACT:
Liquid bioadhesive microemulsions or liposomic dispersions containing proteinic substances, especially calcitonin, that allow the systemic, local or topical administration of drugs by transmucosal route are described. This type of administration shows some considerable advantages of activity, tolerability, dosage individualization and drug stability. The compositions contain proteinic substances, and a polyoxyethylene-polyoxypropylene thermosetting copolymer. At body temperature the viscosity of the compositions is increased and provides increase residence time at the administration site.

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