Method of treating symptoms of microbial infection or sepsis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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A61K 3154

Patent

active

060110309

ABSTRACT:
In accordance with the present invention, a method of treating a patient with symptoms of microbial infection and/or sepsis involves first administering to the patient an antimicrobial amount of a cell wall constituent-inactivating, endotoxin non-releasing, and/or exotoxin-inactivating antimicrobial compound such as Taurolidine and/or Taurultam, without administration of an antibiotic to the patient and prior to administration of such antibiotic. The Taurolidine and/or Taurultam are administered locally or intravenously to the patient to substantially inactivate microbes that are causing the infection. Only after substantially inactivating the microbes causing the infection with the Taurolidine and/or Taurultam, is an antibiotic administered to the patient.

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