3-[(Chlorophenylsulfonyl)methyl]-1,2,4-oxadiazole-5-carboxylic a

Details 3-[(Chlorophenylsulfonyl)methyl]-1,2,4-oxadiazole-5-carboxylic a 3-[(Chlorophenylsulfonyl)methyl]-1,2,4-oxadiazole-5-carboxylic a

1978-07-03

1979-04-10

Rush, Raymond V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260465G, 260564G, 424272, C07D27106

Patent

active

041488016

ABSTRACT:
Disclosed herein are 3-[(chlorophenylsulfonyl)methyl]-1,2,4-oxadiazole-5-carboxylic acid derivatives and 3-[(chlorophenylsulfonyl)ethyl]-1,2,4-oxadiazole-5-carboxylic acid derivatives exhibiting antihypertensive or antiviral activity and having the following formula: ##STR1## wherein: X = 1 or 2; and

REFERENCES:
patent: 2897079 (1959-07-01), DeCat et al.
patent: 3755306 (1973-08-01), Treuner
Palazzo et al., Gazz. Chim. Ital., 90, 1290-1298, (1970).
Behr-Chapter IX, "1,2,4-Oxadiazoles," The Chemistry of Heterocyclic Compounds, 17, 252-253, (1962).
Treuner, Synthesis, 559-560, (Oct. 1972).
Clapp-"1,2,4-Oxadiazoles," Advances to Heterocyclic Chemistry, 20, 97-99.

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