Synthesis of thymosin .alpha..sub.1

Details Synthesis of thymosin .alpha..sub.1 Synthesis of thymosin .alpha..sub.1

1978-06-19

1979-04-10

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

041487885

ABSTRACT:
Thymosin .alpha..sub.1, was chemically synthesized by the fragment condensation of the protected amino terminal tetradecapeptide with the protected carboxyl terminal tetradecapeptide and by solid phase peptide synthesis. Thymosin .alpha..sub.1 is active as an agent which affects regulation, differentiation and function of thymus dependent lymphocytes (T cells).

REFERENCES:
patent: 4002740 (1977-01-01), Goldstein et al.
patent: 4010148 (1977-03-01), Goldstein
patent: 4082737 (1978-04-01), McGregor

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