Novel antibacterial 7-amino-1(substituted cyclopropyl)-1,4-dihyd

Details Novel antibacterial 7-amino-1(substituted cyclopropyl)-1,4-dihyd Novel antibacterial 7-amino-1(substituted cyclopropyl)-1,4-dihyd

1986-02-27

1987-11-10

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514222, 514236, 544 62, 544128, 544363, 546156, 564 1, A61K 31495, C07D40104

Patent

active

047057882

ABSTRACT:
Novel antibacterially active 7-amino-1-(substituted cyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids of the formula ##STR1## in which X.sup.1 and X.sup.2 can be identical or different and represent hydrogen or halogen,

REFERENCES:
patent: 4448962 (1984-05-01), Irikura et al.
patent: 4544658 (1985-10-01), Petersen et al.
patent: 4556658 (1985-12-01), Grohe et al.
patent: 4563459 (1986-01-01), Grohe et al.
patent: 4588726 (1986-05-01), Petersen et al.
Chemical Abstracts, vol. 93, Nov. 24, 1980, No. 21-Abstract No. 198 382n, Koga et al., "Structure-activity Relationships of Antibacterial 6,7- and 7,8-Disubstituted 1-Alkyl-1,4-Dihydro-4-Oxo-Quinoline-3-Carboxylic Acids".
Chemical Abstracts, vol. 98, Jan. 17, 1983, No. 3-Abstract No. 16037b, Lebedev et al., "Quantum-chemical Study of the Electronic Structure of Chlorocyclopropanes and Hydrogenolysis of Carbonchlorine Bonds in Gem-Dichlorocyclopropanes".
Chemical Abstracts, vol. 96, Mar. 15, 1982, No. 11-Abstract No. 85585z, Kyorin Pharmaceutical Co., Ltd., "Piperazinoquinolonecarboxylic Acid Derivatives".
Chemical Abstracts, vol. 102, Jan. 21, 1985, No. 3-Abstract No. 24503s, Irikura, et al., "Quinolinecarboxylic Acid Derivatives".

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