Methods and compositions for isolation and growth of kidney tubu

Details Methods and compositions for isolation and growth of kidney tubu Methods and compositions for isolation and growth of kidney tubu

1995-05-25

2000-05-09

Crouch, Deborah

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435455, 4353201, 435325, 435349, 435350, 435363, 435364, 4353651, 435366, 435374, 435383, 435395, 424 931, 424 932, 424 9321, 514 44, 514 2, C12N 1500, C12N 1563, C12N 500, A61K 3818

Patent

active

060602708

ABSTRACT:
Methods, including culture media conditions, which provide for isolation and purification of renal tubule stem cells and for in vitro kidney tubulogenesis are disclosed. The methods rely on culturing adult kidney cells in a culture media treated with combinations of transforming growth factor-.beta..sub.1, epidermal growth factor, and all-trans retinoic acid.

REFERENCES:
patent: 5429938 (1995-07-01), Humes
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Herzlinger et al. 1994 Developmental Biology 166: 815-818.

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