Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-06-30
2000-05-09
Prouty, Rebecca E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435193, 4352523, 435325, 4353201, 536 231, 536 232, C12N 1554, C12N 910, C12Q 168
Patent
active
060602503
ABSTRACT:
The invention provides three human transferases (HUTRAN) and polynucleotides which identify and encode HUTRAN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HUTRAN.
REFERENCES:
GenBank entry AA203508, Jan. 1997.
GenBank entry F11219, Sep. 1995.
GenBank entry W95847, Nov. 1996.
GenBank entry AA232780, Feb. 1997.
GenBank entry AA401238, May 1997.
GenBank entry AA404282, May 1997.
GenBank entry AA449047, Jun. 1997.
GenBank entry AA677466, Dec. 1997.
GenBank entry AA772088, Jan 1998
ExPASy Enzyme: EC 2.6.1.64.
Perry, S.J. et al., "Isolation and Expression of a cDNA Coding for Rat Kidney Cystosolic Cysteine conjugate .beta.-Lyase", Pharmacol., 43: 660-665 (1993).
Perry, S., et al., "Molecular cloning and expression of a cDNA for human kidney cysteine conjugate .beta.-lyase", FEBS Lett., 360: 277-280 (1995).
Alberati-Giani, D. et al., "Cloning and Characterization of a Soluble Kynurenine Aminotransferase from Rat Brain: Identity with Kidney Cysteine Conjugate .beta.-Lyase", J. Neurochem., 64: 1448-1455 (1995).
Nakatani, Y. et al., ".alpha.-Aminoadipate Aminotransferase of Rat Liver Mitochondria", Biochim. Biophys. Acta., 198: 219-228 (1970).
Buchli, R. et al., "Cloning and Functional Expression of a Soluble Form of Kynurenine/.alpha.-Aminoadipate Aminotransferase from Rat Kidney", J. Biol. Chem., 270: 29330-29335 (1995).
Lin, W.J. et al., "The Mammalian Immediate-early TIS21 Protein and the Leukemia-associated BTG1 Protein Interact with a Protein-arginine N-Methyltransferase", J. Biol. Chem., 271: 15034-15044 (1996).
Abramovich, C. et al., "A protein-arginine methyltransferase binds the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor", EMBO J., 16: 260-266 (1997).
Scott, H.S., et al., "Identification and Characterization of Two Putative Human Arginine Methyltransferases (HRMT1L1 and HRMT1L2)", Genomics, 48: 330-340 (1998).
Cooper, A.J.L. and A. Meister, "Glutamine Transminase K from Rat Kidney", Meth. Enzymol., 113: 344-349 (1985).
Perry, S. et al., (Direct Submission), GenBank Sequence Database (Accession X82224), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 758590; GI 758591).
Buchli, R. et al., (Direct Submission), GenBank Sequence Database (Accession Z50144), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 1050751; GI 1050752).
Scott, H.S. et al., (Direct Submission), GenBank Sequence Database (Acession Y10807), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 1808647; GI 1808648).
Bandman Olga
Corley Neil C.
Gorgone Gina A.
Guegler Karl J.
Hillman Jennifer L.
Incyte Pharmaceuticals Inc.
Muenzen Colette C.
Prouty Rebecca E.
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