Methods for inhibiting bone loss

Details Methods for inhibiting bone loss Methods for inhibiting bone loss

1995-05-10

1996-08-27

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514247, 514305, 514306, 514408, 514415, 514419, 514280, 514212, 514422, 514324, 514403, 514405, 514298, 514297, A61K 3144, A61K 3150, A61K 3140, A61K 31405

Patent

active

055501346

ABSTRACT:
The present invention provides methods of inhibiting bone loss in mammals via the administration to a mammal in need of such treatment an effective amount of a compound from a series of benzoquinolin-3-ones. Such compounds also are sequentially or concurrently coadministered with a bone antiresorptive agent or a bone anabolic agent.

REFERENCES:
patent: 5239075 (1993-05-01), Audia et al.
Anderson, et al., Proc. Natl. Acad. Sci. USA, 87:3640-44 (1990).
Anderson, et al., Nature, 354:159-61 (1991).
Matzkin, et al., Clinical Endocrinol., 37:432-436 (1992).

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