Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1994-01-31
1996-08-27
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514292, 546 85, 546 86, 546 87, A61K 3144, A61K 31675, C07F 958, C07D47104
Patent
active
055501184
ABSTRACT:
Selected acid functional polyhydronorharman type derivatives effective as thromboxane synthase inhibitors having the formula: ##STR1## where R.sub.1 and R.sub.2 are monovalent radicals, --(L.sub.a)-- is a linking group of 4 to 8 chain atoms, and A is an acidic group.
REFERENCES:
patent: 2850501 (1958-09-01), Voegtli
patent: 4855295 (1989-08-01), Biere et al.
patent: 5066649 (1991-11-01), Hamminga et al.
patent: 5328905 (1994-07-01), Hamminga et al.
Jakubowski Joseph A.
Palkowitz Alan D.
Sigmund Sandra K.
Benjamin Roger S.
Boone David E.
Eli Lilly and Company
Rotman Alan L.
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