Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1994-12-29
1996-08-27
Datlow, Philip I.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514220, 540542, 540557, A61K 3155, C07D48714
Patent
active
055501176
ABSTRACT:
Disclosed are novel dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the treatment of HIV-1 infection. An exemplary species is 6-chloro-11-cyclopropyl-4-methyl-11H-dipyrido[3,2-b:2',3'-e][1,4]diazepine , which has the following chemical structure: ##STR1##
REFERENCES:
patent: 5087625 (1992-02-01), Hargrave et al.
patent: 5366972 (1994-11-01), Hargrave et al.
J. Benditt and J. Cohen, Science, vol. 260, May 28, 1993, pp. 1253-1255.
Sandstrom et al., Review Article in Drugs, 34, pp. 373-390 (1987).
Yarchoan et al, Aids: Modern Concepts and Therapeutic Challanges, Marcel Dekker Inc., pp. 335-360 (1987).
Hahn et al, "Nucleotide Dimers as Anti-Human Immuno-deficiency Virus Agents," in Nucleotide Analogues are.
Antiviral Agents, Martin ed., Amer. Chem. Soc., pp. 156-159 (1989).
March, Advanced Organic Chem., 3rd ed (1985), pp. 527-529.
Adams Julian
Cullen Ernest
Grozinger Karl G.
Hargrave Karl D.
Pal Kollol
Boehringer Ingelheim Pharmaceuticals Inc.
Datlow Philip I.
Devlin Mary-Ellen M.
Raymond Robert P.
Stempel Alan R.
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