Molecular farming

Details Molecular farming Molecular farming

1993-12-08

1996-08-27

Fox, David T.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

435 691, 435 6951, 4351723, 536 235, 800205, 800255, 800DIG17, C12N 1512, C12N 1520, C12N 1582, C12N 1584

Patent

active

055500382

ABSTRACT:
Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a terminator functional in a plant host. The construct is introduced into a plant cell to become integrated into the plant genome for expression in the plant cells or plants. The plant cells may be harvested and the mammalian protein isolated in physiologically active form.

REFERENCES:
patent: 4956282 (1990-09-01), Goodman et al.
Shaw et al. 1983. Gene 23: 315-330.
Koncz et al. 1984. Embo J. 3: 1029-1037.
Goodman et al. 1987. Science 236: 48-54.

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