Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-10-20
1976-11-30
Rollins, Alton D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260295T, 424263, 424269, C07D48704
Patent
active
039949419
ABSTRACT:
A process for the production of compounds of the formula III: ##SPC1##
wherein ring A is unsubstituted or substituted by fluoro, chloro, bromo, trifluoromethyl, or nitro, and wherein Ar is phenyl, o-chlorophenyl, o-fluorophenyl, or 2-pyridyl, is claimed in which the starting compound is the corresponding 1-methyl-6-substituted-4H-s-triazolo[4,3-a][1,4]-benzodiazepine. Compound III is converted to compoud IV or V, the corresponding 1-(2-aminoethyl)-6-substituted-4H-s-triazolo[4,3-a][1,4]benzodiazepines, which are known antidepressant and anti-anxiety agents.
REFERENCES:
patent: 3842090 (1974-10-01), Gall et al.
patent: 3882139 (1975-05-01), Gall et al.
Berneis Hans L.
Rollins Alton D.
The Upjohn Company
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