Spiro(5H-dibenzo[a,d]cyclohepten-5-oxazolin-2-ones) and their 10

Details Spiro(5H-dibenzo[a,d]cyclohepten-5-oxazolin-2-ones) and their 10 Spiro(5H-dibenzo[a,d]cyclohepten-5-oxazolin-2-ones) and their 10

1975-06-17

1976-11-30

Rush, Raymond V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D26322

Patent

active

039949184

ABSTRACT:
The invention discloses compounds of the class of 5-substituted-5H-dibenzo[a,d]cycloheptenes which are 5-hydrazinoalkyl- or 5-aminoalkyl-5H-dibenzo[a,d]cyclohepten-5-ols, or their 10,11-dihydro derivatives. The compounds are pharmaceutically active and useful, for example, as anti-convulsants and tranquilizers. A key intermediate are compounds which are a spiro[5H-dibenzo[a,d]cyclohepten-5-oxazolin-2-one] which are subjected to alkaline hydrolysis to obtain the compounds of the invention.

REFERENCES:
cope et al., J. Am. Chem. Soc., 78, 1012-1013 (1956).

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