Preparation of substituted oxazoles

Details Preparation of substituted oxazoles Preparation of substituted oxazoles

1975-01-06

1976-11-30

Rush, Raymond V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260307DB, 260471A, 260476R, C07D26332

Patent

active

039949150

ABSTRACT:
Benzocycloheptaoxazolones are prepared by a multi-step process starting with a lower alkyl ester of a 3-oxo-5-phenylvaleric acid. The compounds are useful as anti-inflammatories and as intermediates in the preparation of pharmaceutically useful compounds.

REFERENCES:
treibs et al., Berichte 84, 671-672 (1951).
Morrison et al., "Organic Chemistry", Allyn & Bacon, Inc., (1959), pp. 480, 484.
Elderfield, "Heterocyclic Compounds", vol. 5, John Wiley & Sons, Inc. (1957), pp. 302-303.
Smith, "Open-Chain Nitrogen Compounds", vol II, W. A. Benjamin, Inc. (1966), pp. 60-61.

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