Pyrimidinedione derivatives and antiarrhythmic agents containing

Details Pyrimidinedione derivatives and antiarrhythmic agents containing Pyrimidinedione derivatives and antiarrhythmic agents containing

1992-11-02

1994-07-26

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544295, 544311, 544312, 514269, A61K 3150, A61K 31505, C07D40304, C07D23942

Patent

active

053327390

ABSTRACT:
Pyrimidinedione derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 is so linked with each other as to make an alkylene chain and thus form a heterocyclic structure, A, R.sup.3, R.sup.4, X.sup.1, X.sup.2 and X.sup.3 are substituents, respectively, and n is 2 or 3 have a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain and a heterocyclic ring having two nitrogen atoms. These compounds are useful for a medical treatment of cardiac arrhythmias.

REFERENCES:
patent: 4216314 (1980-08-01), Raabe et al.
patent: 5008267 (1991-04-01), Katakami et al.

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