Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis
Patent
1993-10-08
1996-08-27
Dodson, Shelley A.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
4352402, 43524021, 514 12, 600 36, 604 6, 604 35, 604 48, 604319, 623 1, 623 12, A61F 200, C12N 500, A61K 3800, A61M 100
Patent
active
055496741
ABSTRACT:
A novel cell seeded hollow fiber bioreactor is described as a potential bioartificial kidney. Renal cells are seeded along a hollow fiber in a perfused bioreactor to reproduce the ultrafiltration function and transport function of the kidney. Maintenance of tissue specific function and ultrastructure suggest that this bioreactor provides an economical device for treating renal failure as well as studying renal tubululogenesis in vitro.
REFERENCES:
patent: 5035708 (1991-07-01), Alchas et al.
patent: 5192747 (1993-03-01), Krstenansky
JP, A, 61, 115569 (Terumo Corp) Jun. 3, 1986 (Abstract).
Artificial Organs, 13(1): 58-65, 1989 (IP) "Renal Epithelial-Cell Controlled Solute Transport Across Permeable Membranes as the Foundation for a Bioartificial Kidney".
Database WPI, Derwent Publications, AN-86-180755/28, JP-61-115569, Jun. 3, 1986.
Deborah A. Cieslinski and H. David Humes, "Tissue Engineering Of A Bioartificial Kidney", Biotechnology and Bioengineering, vol. 43, pp. 678-681, (1994).
Cieslinski Deborah A.
Humes H. David
Dodson Shelley A.
The Regents of the University of Michigan
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