Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-01-15
1990-04-17
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514452, 514450, 514456, 514464, 514465, 514466, 514469, 514470, 548253, 549 10, 549 11, 549350, 549362, 549399, 549355, 549407, 549462, 549445, A61K 3135
Patent
active
049180924
ABSTRACT:
Compounds having the formula I: ##STR1## are antagonists of leukotrienes of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic and anti-inflammatory agents.
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Samuelsson, B. Science vol. 220, pp. 568-575 (1983).
Bailey, D. M. Annual Reports in Medicinal Chemistry pp. 203-217 (1982).
Frenette Richard
Kakushima Masatoshi
Young Robert N.
Hollrah Glennon H.
Lopez Gabriel
Merck Frosst Canada Inc.
Owens Amelia A.
Pfeiffer Hesna J.
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