Pharmaceutical compositions and medical uses of dioxopiperidine

Details Pharmaceutical compositions and medical uses of dioxopiperidine Pharmaceutical compositions and medical uses of dioxopiperidine

1989-03-14

1990-04-17

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

049180843

ABSTRACT:
Phenyl-3-aminoalkyl-4-methyl-2,6-dioxopiperidines of the Formula I ##STR1## wherein: R.sub.1 represents methoxy, ethoxy or hydroxy,

REFERENCES:
patent: 3963729 (1976-06-01), Gittos
patent: 4461771 (1984-07-01), Gittos
Chem. Abst. 81-120488J (1974).
Conn's Current Therapy, 1986, pp. 924-925.
Gray, J. A., The Neuropsychology of Anxiety, Clarendon Press (1982), pp. 399-407, British National Formulary (7th edition, 1984), pp. 128-135 and 144-151.
The Extra Pharmacopoeia, Martindale, pp. 1504-1563, pp. 110-134 (28th ed.), Liebowitz et al., Psychopharmocology Bulletin, vol. 17 (1983), 3, 159-160.
Briley et al., Brit. J. Pharma. 1986, 87, 217p, Lydiard et al., Am. J. Psychiatry, vol. 144 (1987), 5, 664-5.
Liebowitz et al., J. Clin. Psychopharm., vol. 6, 1, 13-20, Breier et al., Atch Gen Psychiatry, vol. 41, Dec. 1984, p. 1129.
Liebowitz et al., Psychopharmacology Bulletin, vol. 22 (1986), 3, 792-6, Clerc et al., Am. J. Psychiatry, 143:2, Feb. 1986.
Brogden et al., Drugs (1981), 21, 415-417.

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