Method and vessel for separation of cryoglobin

Details Method and vessel for separation of cryoglobin Method and vessel for separation of cryoglobin

1986-10-31

1990-04-17

Jones, W. Gary

Liquid purification or separation

Processes

Making an insoluble substance or accreting suspended...

2103216, 210472, 210515, 210539, 210782, 210789, 422101, 422102, 424101, 494 37, 530380, 530383, 530830, 604410, B01D 2126

Patent

active

049178040

ABSTRACT:
A set for the isolation of cryoprecipitate includes a hollow vessel with a closed first end, a second end and a longitudinal axis, and a nipple extending from and closing the second end, said nipple enclosing a volume of approximately 2 to 5 percent of the volume of the hollow vessel. In one embodiment, the vessel is formed of a semi-rigid material and the first end is closed by a cap containing a micro-porous filter for venting the vessel. In another or further embodiment, the nipple has a tapered tip portion which may be sliced off to permit extrusion of the isolated cryoprecipitate by squeezing the vessel. In a different further embodiment, the nipple has a twist-lockable connector, for attachment to a syringe or to an applicator tip. In yet another embodiment a piston mounts on the cap within the vessel for directly extruding separated cryoprecipitate from the nipple. Preferably the set includes plural vessels, each connected to a common sterile docking connector and having a total volume of approximately 250 ml, for processing the plasma from one unit of whole blood. Methods for the isolation of cryoprecipitate using a set according to the invention, and for the surgical application of the isolated precipitate are shown.

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"Now the Way is Clear . . . with the Cutter Leukotrap Platelet Pooling System", Miles Laboratories (1985), CB-676.

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