Prostaglandin E1 derivatives as pharmaceutically active agents,

Details Prostaglandin E1 derivatives as pharmaceutically active agents, Prostaglandin E1 derivatives as pharmaceutically active agents,

1990-02-22

1993-06-15

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

A61K 31557

Patent

active

052198855

ABSTRACT:
The invention describes prostaglandin E1 derivatives as pharmacologically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration.

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Webster's Third New International Dictionary Unabridged (1963).
Creutzig, "Prostaglandins and their effects upon diseases of blood vessels", Med. Klin., 81, 395 (1986).
Demol et al., "Prevention of the acetylsalicylic acid-induced changes of the gastric potential difference by the new synthetic prostaglandin E. analogue Rioprostil", Arezneim.-Forsch./Drug Res., 36, 1406 (1986).
Sim et al., "The effect of prostaglandin E, incorporated in lipid microspheres on thrombus formation and thrombus disaggregation and its potential to target to the site of vascular lesions", Arzneim.-Forsch./Drug Res., 36, 1206 (1986).
Forstermann et al., "Elimination from the circulation of cats of 6-Keto-prostaglandin E, compared with prostaglandins E.sub.2 and I.sub.2 ", J. Pharm. Pharmacol. 35, 724 (1983).
Chemical Abstracts, vol. 72, No. 13, Ser. No. 70628w, Mar. 30, 1970, p. 306.
Chemical Abstracts, vol. 95, No. 25, Ser. No. 215404g, Dec. 21, 1981, p. 74.

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