Certain optically active substituted 3-pyrraidine acetic acid de

Details Certain optically active substituted 3-pyrraidine acetic acid de Certain optically active substituted 3-pyrraidine acetic acid de

1990-11-30

1991-12-10

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546123, 546156, 548566, 548567, C07D20708

Patent

active

050720015

ABSTRACT:
Optically pure isomers of 7-[3-(1,1-dialkylmethyl-1-amino)-1-pyrrolidinyl]quinolones and naphthyridones as therapeutically active and safe antibacterial agents are described, as well as pharmaceutical compositions thereof, and a method of treating bacterial infections therewith. Also described is a method of manufacture of the quinolones and naphthyridones as well as the starting materials, the optically pure pyrrolidine moieties for attachment at the 7-position.

REFERENCES:
patent: 4665079 (1987-05-01), Culbertson et al.

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