Method of preparing bicyclic tetrahydroxylated pyrrolizidines

Details Method of preparing bicyclic tetrahydroxylated pyrrolizidines Method of preparing bicyclic tetrahydroxylated pyrrolizidines

1990-09-24

1991-06-25

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D48710

Patent

active

050268708

ABSTRACT:
Novel bicyclic tetrahydroxylated pyrrolizidines are disclosed which are inhibitors of glycosidase enzymes. A preferred inhibitor is 1.alpha.,2.alpha.,6.alpha.,7.alpha.,7.alpha..beta.-1,2,6-7-tetrahydroxypyr rolizidine. It is synthesized from D-glycero-D-gulo-heptono-1,4-lactone.

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