Novel 1-alkyl-substituted 1,4-dihydropyridinelactone anti-diabet

Details Novel 1-alkyl-substituted 1,4-dihydropyridinelactone anti-diabet Novel 1-alkyl-substituted 1,4-dihydropyridinelactone anti-diabet

1989-11-13

1991-06-25

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546116, A61K 31435, C07D491048

Patent

active

050267140

ABSTRACT:
Novel blood sugar-lowering dihydropyridinelactones of the formula ##STR1## in which R represents halogen, C.sub.1 -C.sub.10 -alkyl, C.sub.1 -C.sub.10 -alkoxy, C.sub.1 -C.sub.10 -alkylthio, C.sub.1 -C.sub.10 -alkylsulphinyl, C.sub.1 -C.sub.10 -alkylsulphonyl, cyano, C.sub.1 -C.sub.6 - mono- or polyfluoroalkyl, C.sub.1 -C.sub.6 -mono- or polyfluoroalkoxy or nitro,

REFERENCES:
patent: 4048171 (1977-09-01), Bossert et al.
patent: 4145432 (1979-03-01), Sato
patent: 4253248 (1985-07-01), Franckowiak et al.
Schramm et al., Nature vol. 303, Jun. 9, 1983.

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