Process for preparing hyaluronic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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4352521, 435244, 536 551, C12P 1904, C12N 138, C12N 100, C08B 3700

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active

050717510

ABSTRACT:
A process for producing a hyaluronic acid can be provided steadly, with a greatly improved productivity and at an inexpensive cost by incubating a hyaluronic acid-producing microbe in a culture medium formed by adding a blood serum or a bacteriolytic enzyme and/or a surfactant, accumulating and isolating the hyaluronic acid.

REFERENCES:
patent: 3063914 (1962-11-01), von Polnitz
patent: 3929571 (1975-12-01), Kubota
patent: 3988205 (1976-10-01), Boguth
Buchanan et al., Veterinary Microbiology, vol. 7, pp. 19-33, 1982.
"Bergeys Manual of Determinative Microbiology", 1984, p. 498.

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