Pharmaceutical combination for treatment of bone-wasting disease

Details Pharmaceutical combination for treatment of bone-wasting disease Pharmaceutical combination for treatment of bone-wasting disease

1990-01-12

1991-12-10

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424434, 424449, 424464, 424606, 424673, 514389, A61F 1300, A61K 3316, A61K 31415

Patent

active

050716557

ABSTRACT:
A pharmaceutical composition for increasing bone mass and preventing loss of bone mass is provided, comprising a fluoride source and a mitogenic hydantoin in combination with a pharmaceutically acceptable carrier, in which the fluoride source provides a molar ratio of fluoride ion to hydantoin in the composition of from about 0.1:1 to about 100:1. The combination is administered to a vertebrate, typically in the form of an orally administratable tablet or capsule.

REFERENCES:
patent: 4386100 (1983-05-01), Brittain et al.
patent: 4501754 (1985-02-01), Wechter et al.
patent: 4686104 (1987-08-01), Bockman et al.
patent: 4726952 (1988-02-01), Walsdorf et al.

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