Spherical granules having core and their production

Details Spherical granules having core and their production Spherical granules having core and their production

1988-01-14

1991-06-25

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424458, 424461, 424468, 424480, 424489, 424490, 424479, 424493, 424497, 514925, A61K 916, A61K 936, A61K 962

Patent

active

050265601

ABSTRACT:
The spherical granules having a core coated with spraying powder containing a drug and low substituted hydroxypropylcellulose, because of their excellent hardness, can be coated further evenly, (e.g. sustained release coating, gastric coating, enteric coating), and at the time the granules are excellent in disintegration.

REFERENCES:
patent: 3477864 (1969-11-01), Tuji
patent: 4226849 (1980-10-01), Schor
patent: 4695591 (1987-09-01), Hanna et al.
patent: 4758437 (1988-07-01), Sonobe et al.
patent: 4786505 (1988-11-01), Lovgren et al.
Drug Development and Industrial Pharmacy, 11(8), 1523-1541 (1985).

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