Stereoselective process for preparing optically active alpha, be

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549 60, 549 73, 549267, 549274, 549473, 549483, 549498, 548517, 548518, 548562, 568319, 568386, 568397, 568435, 568483, 546174, 546315, 546284, 546283, 546281, 546275, C07D31734

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049736965

ABSTRACT:
A stereoselective process is described for preparing optically active alpha,beta-disubstituted carbonyl compounds, comprising forming an acetal between an alpha,beta-unsaturated aldehyde or ketone and tartaric acid or a derivative thereof, halogenating the product thus obtained, and restoring the carbonyl compound.

REFERENCES:
patent: 4764641 (1988-08-01), Castaldi et al.
patent: 4764692 (1988-08-01), Castaldi et al.

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