Polycyclic imidazoles

Details Polycyclic imidazoles Polycyclic imidazoles

1975-07-07

1976-10-19

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

260309, C07D23502

Patent

active

039871835

ABSTRACT:
Disclosed are certain polycyclic imidazoles which are effective in inhibiting indoleamine-N-methyl transferase and thus useful in the treatment of mental aberrations, such as schizophrenia. Also disclosed are processes for the preparation of such imidazoles; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions.

REFERENCES:
patent: 3624101 (1971-11-01), Sulkowski et al.
patent: 3814707 (1974-06-01), Moller et al.
Chemical Abstracts Subject Index E-O for vols. 11-20, p. 4443, (1917-1926).
Chemical Abstracts Subject Index Copper-I for vols. 31-40, p. 6580, (1937-1946).
Chemical Abstracts Subject Index H-MH for vols. 51-55, p. 60505, (1957-1961), (Sixth Collective Index).
Chemical Abstracts Subject Index Hy-Lit for vols. 56-65, p. 11,663s, (1962-1966), (Seventh Collective Index).
Chemical Abstracts Subject Index, Indene-Livei for vols. 66-75, p. 15770S, (1967-1971), (Eighth Collective Index).
Chemical Abstracts Chemical Substance Index (E-O), vol. 77, p. 1991CS (July-Dec. 1972).
Chemical Abstracts Chemical Substance Index (E-N), vol. 78, p. 2079CS (Jan.-June 1973).
Chemical Abstracts Chemical Substance Index (A-I), vol. 79, p. 1861CS (July-Dec. 1973).
Chemical Abstracts Chemical Substance Index (E-O), vol. 80, pp. 1977CS, 1982CS, (Jan.-June 1974).

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