Dialkanolamine derivatives

Details Dialkanolamine derivatives Dialkanolamine derivatives

1985-09-30

1987-03-10

Hines, Robert V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

2605011, 26050118, 514425, 514648, 564316, C07C 8728, C07D20700

Patent

active

046492046

ABSTRACT:
Dialkanolamines and nontoxic pharmaceutically-acceptable acid-addition salts of the compounds of the following formula ##STR1## wherein R.sub.1 is hydrogen lower alkyl, or fluoro; R.sub.2 is hydrogen or lower alkyl; R.sub.3 and R.sub.4 are the same or different and selected from the group consisting of hydrogen or lower alkyl or R.sub.3 and R.sub.4 together define a chemical bond directly linking the two alkanol chains so as to form a pyrrolidine ring; Ar, is phenyl or thienyl or phenyl substituted with one to three substituents selected from the group consisting of lower alkyl and halo; and Ar.sub.2 is phenyl and phenyl substituted with one to three substituents selected from the group consisting of lower alkyl and halo which have antidepressant activity.

REFERENCES:
patent: 3157656 (1964-11-01), Krapcho
patent: 3342829 (1967-09-01), Schorr et al.
patent: 3467675 (1969-09-01), Petersen et al.
patent: 3700680 (1972-10-01), Kaneko et al.
patent: 3794645 (1974-02-01), Pieper et al.
patent: 3855294 (1974-12-01), Podesva et al.
patent: 3895057 (1975-07-01), Kaneko et al.
Kloska, "Jour fur Prakische Chemie", vol. 311, pp. 520-522 (1969).
Kjaer et al., "Peta Chemica Scandi", vol. 5, pp. 1145-1150 (1951).
Cattaneo et al., "Farmaco. Sci. Edit. (Italy)", vol. 17, pp. 308-319 (1982).

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