Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-07-08
1987-03-10
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514210, 514212, 514330, 514423, 540 1, 540607, 546245, 546226, 548540, A61K 31445, C07D21164
Patent
active
046491473
ABSTRACT:
This invention relates to 1-(alkenoyl)azacycloalkyl carboxylic acids and derivatives that prevent or reduce the degradation of elastin and other proteins and that thereby prevent or retard the disease states caused by said degradation.
REFERENCES:
patent: 3248396 (1966-04-01), Skav et al.
patent: 3621043 (1971-11-01), Seki et al.
patent: 4118500 (1978-10-01), Mitzlaff et al.
patent: 4208421 (1980-06-01), Morelle et al.
Sandberg, L. et al., New England J. Med., 304, 566-579 (1981).
Werb, Z. et al., J. Investigative Dermatology, 79, 154s-159s (1982).
Rinaldo, J. et al., New England J. Med., 306, 900-909 (1982).
Nakajima, K. et al., J. Biol. Chem., 254, 4027-4031 (1979).
Reilly, C. et al., J. Biol. Chem., 257, 8619-8622 (1982).
Tonnesen, M. et al., J. Clin. Invest., 69, 25-30 (1982).
Wong, P. et al., Biochem. Biophys. Res. Commun., 96, 1449-1454 (1980).
Turino, G. et al., Amer. J. Med., 57, 493-503 (1974).
Boudier, C. et al., J. Biol. Chem., 256, 10256-10258 (1981).
McDonald, J. et al., J. Biol. Chem., 255, 8848-8858 (1980).
Fuller, G., J. Med. Chem., 24, 651-658 (1981).
Kelley, J. et al., J. Lab. Clin. Med., 96, 954-964 (1980).
Mueller Richard A.
Partis Richard A.
G. D. Searle & Co.
Henderson Richard E. L.
McDonnell John J.
Schwartz Richard A.
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