Methods for isolating mutant microorganisms from parental popula

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

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435182, 435243, 435 39, C12P 124

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046491090

ABSTRACT:
A method for isolating a mutant microorganism is described. The method comprises the steps of: (a) separately microencapsulating in a semi-permeable membrane each or a small number of microorganisms from a microorganism population containing said mutant; (b) growing said microencapsulated microorganisms including treating to induce a detectable difference between microcapsules containing mutant microorganisms and those containing non-mutant microorganisms; and (c) separating said microcapsules containing mutant microorganisms from those containing non-mutant microorganisms based on said difference.

REFERENCES:
patent: 4255411 (1981-03-01), Lim et al.
patent: 4278761 (1981-07-01), Hastings et al.
patent: 4352883 (1982-10-01), Lim
patent: 4391909 (1983-07-01), Lim
patent: 4401755 (1983-08-01), Weaver
patent: 4401762 (1983-08-01), Tellier et al.
patent: 4407957 (1983-10-01), Lim
patent: 4409331 (1983-10-01), Lim
Lehinger, Biochemistry, 2nd ed., 1975, Worth Publishing, New York, pp. 157-159.

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