Method for treatment of antidiuresis employing serine derivative

Details Method for treatment of antidiuresis employing serine derivative Method for treatment of antidiuresis employing serine derivative

1985-09-30

1987-03-03

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514869, A61K 31195

Patent

active

046475877

ABSTRACT:
Diuretics containing an efficient amount of L- or DL-threo-3-(3,4-dihydroxyphenyl)-serine or a pharmaceutical acceptable salt thereof are applied orally or parenterally. They are effected particularly to anasarca patients. They will also be effective to myxedema, Addison's disease and other ADH-excessive syndrome patients. They are applied in the form of tablet, capsules, syrup, suspension or liquid.

REFERENCES:
patent: 3920728 (1975-11-01), Hegedus et al.
patent: 4330558 (1982-05-01), Suzuki et al.
patent: 4497826 (1985-02-01), Narabayashi et al.
patent: 4529603 (1985-07-01), Mori et al.
J. Pharm. Pharmac., 33, 772-777 (1981), Pressor Effect of L-Threo-3,4 Dihydroxyphenylserine in Rats.
J. Pharm. Pharmac., 30, 456-458 (1978), Positive Chronotopic Effect of Threo-3,4 Dihydroxyphenylserine as a Precursor of Noradrenaline in Rat Isolated Atria.
J. Pharmacol. Exp. Ther., 193, 523-532 (1975)* The Stereoisomers of 3,4-Dihydroxyphenylserine as Precursors of Norepinephrine.

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