Anti-spasmodic agents having three branch chains

Details Anti-spasmodic agents having three branch chains Anti-spasmodic agents having three branch chains

1985-02-20

1987-03-03

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540450, 540467, 540470, 540544, 540553, 540575, 540610, 514210, 548950, 514211, 514212, 514218, 514228, 514255, 514315, 514317, 514320, 514365, 514375, 514385, 514428, 514513, 544 581, 544158, 544380, 544399, 546205, 546238, 546248, 548146, 548215, 548300, 548573, 558256, A61K 3154, A61K 31265, C07C153017, C07D27912

Patent

active

046475621

ABSTRACT:
A new class of anti-spasmodic compounds having three branch chains is provided. These compounds have the general formula: ##STR1## where R.sub.1, R.sub.2 and R.sub.3 are saturated straight chain or branched alkyl groups contained from 1 to 8 carbon atoms, and are separated or linked to one another to form an aliphatic ring system. k is an integer from 0 to 5, and the total number of carbon atoms in R.sub.1 plus R.sub.2 plus R.sub.3 plus k are equal to or less than 12. Furthermore, l is an integer from 1 to 3, m is an integer from 1 to 3, n is an integer from 1 to 3, and X may be nonexistent or may be O, S, NH or CH.sub.2 or salts thereof. However, when X is nonexistent the terminal group in both the m chain and the n chain is a methyl group.

REFERENCES:
patent: 2390555 (1945-12-01), Richardson
patent: 3671527 (1972-06-01), Krimmel

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