Therapeutic nucleosides

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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C07H 1700

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active

050649469

ABSTRACT:
Several novel 3-azido-2,3-dideoxy-.beta.-D-erythro-pentofuranosyl derivatives of substituted pyrimidinones having antiretroviral, especially anti-AIDS, activity are described.

REFERENCES:
patent: 4594339 (1986-06-01), Lopez et al.
patent: 4681933 (1987-07-01), Chu et al.
DeClercq, Expt. Clin. Pharm. 2(5):253-63, 1980.
Imazawa et al., J. Org. Chem. 43(15):3044-3048, 1978.
Yarchogn et al., The Lance, Mar. 15, 1986, pp. 575-580.

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