Process for the purification of serum albumin

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

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435 712, 530364, 935 11, 935 12, C07K 328, C12N 1514

Patent

active

049904477

ABSTRACT:
Recombinantly produced serum albumin is purified in a series of steps, initially employing an alkaline precipitation, optionally followed by incubation with an anion exchange absorbent, followed by affinity chromatography employing a hydrophobic solid phase and using a water-soluble lipid anion as desorbens in the aqueous phase.

REFERENCES:
patent: 4086222 (1978-04-01), Lindquist et al.
patent: 4228154 (1980-10-01), Fisher et al.
Chem. Abstracts, 91:119043k, 1979 (Hori).
Biochimica et Biophysica Acta 372: 218-224 (1974), Wichman et al.

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