N-substituted imidazoles and their use in pharmaceutical agents

Details N-substituted imidazoles and their use in pharmaceutical agents N-substituted imidazoles and their use in pharmaceutical agents

Filed on

1989-03-31

Date issued

1991-09-03

Examiner

Lee, Mary C.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Having -c-, wherein x is chalcogen, bonded directly to...

Other Related Categories

514397, 548335, 548336, C07D23360, C07D23361, A61R 31415

Type

Patent

Status

active

Patent number

050455583

Description

ABSTRACT:
The invention relates to N-substituted imidazoles, processes for their production as well as their use in pharmaceutical agents. The compounds according to the invention have aromatase-inhibiting properties.

REFERENCES:
patent: 4226878 (1980-10-01), Iizuka et al.
patent: 4405634 (1983-09-01), Thorogood
patent: 4731370 (1988-03-01), Watanabe et al.
patent: 4778817 (1988-10-01), Lau et al.
patent: 4916144 (1990-04-01), Strehlke
Chemical Abstracts, 83:157710t(1975)[K. Baggaley, et al., J. Med. Chem. 1975, 18(8), 833-6].
Chemical Abstracts, 104:224901y (1986)[G. Wess, et al., Ger. Offen. 3,424,944, 2/6/86].
Chemical Abstracts, 108:17777e (1988)[S. Nishimura et al., JPN. Kokai Tokkyo Koho 62, 205,002, 9/9/87].

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